Abnormal AMH but Normal FSH

I have been diagnosed with PCOS since I was 20. I have had very irregular periods, whether none at all for a year or bleeding continually for a year. I have been working with an OBGYN trying to get pregnant off and on for last last 8 years. No luck. I have done the maximum dose of 250mg cycle with Clomid and 150mg with Femara. Either have worked, still no ovulation. I recently asked if there were any other testing that may shed some light on my infertility issues. He tested my FSH and it came back 3.5. Then they tested my AMH, it was 31. My doctor literally acted like he knew it was completely abnormal, he specified that the highest in his career he has dealt with was 15. I'm worried. I don't want to be wasting my time with this doctor if his answer is literally "I don't know" when i'm needing more answers not questions. Please let me know if anyone can shed some light on what 31 value on an AMH lab could mean.

Thank you for your time.

Thanks,
Cassie

Our Expert's Answer

This information was published 2 years, 7 months ago and was correct at the time of publication. It may not reflect our current practices or regulations.

Please note that all the answers we give are on a generic basis only, as we cannot provide more in-depth answers without access to your medical history. If you need a more detailed response, tailored to you, we would recommend a consultation with one of our Fertility Specialists for more comprehensive medical advice.

 

Results of anti-Mullerian hormone test can be confusing. To recap having been diagnosed with PCOS, you were found resistant to Clomid and Femara. If your AMH level is still measured high it could means that your ovaries are still in PCOS-mode but also means you are having good ovarian egg reserve.

You should check your AMH report, 31 pmol/l is rather in the normal range and not particularly high. If it is 31 ng/ml then it is high. In this case a pelvic ultrasound scan would normally be recommended to check your ovaries.

There are several approaches to deal with clomid-resistant polycystic ovarian syndrome and if you would like further support, please contact us on 0161 300 2730 if you would like to arrange consultation. We are also able to arrange a Skype or telephone consultation if you prefer where we could discuss and review your test results and treatment reports.