What is Endometrial Receptivity Array?
Endometrial Receptivity Array (ERA) is a genetic test performed prior to frozen embryo transfer in highly-selected patients. This test aims to identify the best time for your embryo transfer, based on genetic testing to identify the window of implantation.
ERA may be advised if:
- You’ve had repeated implantation failure
- You’ve had failed IVF cycles despite the transfer of good quality embryos
We are not completely sure whether the test improves the chance of success with IVF.
However, there are studies showing that the information available from an ERA test may benefit some groups of women.
How can ERA help me?
Your uterus is usually most receptive to an embryo around days 19-21 of your menstrual cycle, which is when embryo transfer is typically carried out.
But in some women, this window of implantation may in fact be earlier or later, and it is thought that this may lead to failure of IVF.
ERA is a test that allows us to assess whether or not the uterus is receptive at the usual time. Based on the results of the test, we can alter the time of embryo transfer, in the hope of increasing the chance of an embryo implanting successfully.
We will perform an endometrial biopsy in a cycle where you take hormones in a similar way to a frozen embryos transfer cycle, timed for when we think your uterus should be most receptive.
Tissue is preserved
The endometrial tissue is immediately transferred into a tube which contains a fluid that facilitates the preservation of the tissue and sent to a specialist genetics laboratory.
The laboratory analyses the genes involved in embryo receptivity to determine if your uterus is optimum for transfer. We then use this information to decide when your embryo transfer should be carried out in a future frozen embryo transfer cycle.
Add-ons are optional extras that you may be offered on top of your normal fertility treatment, often at an additional cost.
Some clinics may include certain add-ons with their treatment packages as standard whilst others charge separately, this add-on is in an option extra not included as part of your treatment and can be paid for as an extra part of your treatment, at Manchester Fertility we do charge for this add-on.
Your doctor will be able to provide you the complete information and risk associated with any of these add-ons, we offer these add-ons after a full discussion with our experts and after your specific individual circumstances have been considered.
We fully support the HFEA’s view on all add-ons, please see here for more information.
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