Kind advice solicited regarding IVF failure.

Sir, our history is as follows –
Married since year 2004 (approx. 9 years).
Wife - Age 33 years, suffered genital TB, Taken ATT for 2 years, Fallopian tubes cornual blocked, ovaries and uterus – normal but endometrium thin 6mm even after taking hormones becomes irregular, prognosis very poor.
Husband - Age 37 years, ICSI done. Sperm count and mobility - Normal
Karyotyping of blood sample of both the partners found to be normal.
IVF Treatment history - we have had three failed IVF cycles. First ET through wife and other two with surrogate.
In first ivf (year - 2008) 20 grade-A embryo, four embryo transferred in wife but pregnancy test negative (INKUS IVF centre - Mumbai, Dr. Indira Hinduja), endometrium thickness might be the cause of failure, no FET tried.
Second ivf in 2011 in Lucknow (Ajanta ivf centre, Dr. Geeta Khanna) through surrogate, 13 eggs retrieved, 9 embryos developed without ICSI, four A grade, result – negative, unfortunately surrogate suffered from medical issues (thyroid, TB, fluid in uterus before ET).
Third ivf in year 2013 again in INKUS ivf centre Mumbai. 12 A grade embryos developed through ICSI, Three transferred and 9 freezed. Fresh ET through surrogate - test positive but miscarried after 6 weeks. Then FET through surrogate (this time only 4 embroyes thawed successfully, 1 a grade and 3 B grade), test positive but no heartbeat found after 7 weeks, featal pole exists.
Request - Sir, based on above facts we request you to kindly suggest us the future course of action.

Sir, you are requested to kindly suggest us the best and also the cost and procedure for that option. Thanking you, With regards.

Our Expert's Answer

This information was published 10 years, 6 months ago and was correct at the time of publication. It may not reflect our current practices or regulations.

Please note that all the answers we give are on a generic basis only, as we cannot provide more in-depth answers without access to your medical history. If you need a more detailed response, tailored to you, we would recommend a consultation with one of our Fertility Specialists for more comprehensive medical advice.

I am very sorry to hear your treatment history however we would not be able to offer any different treatment at Manchester Fertility.