Is it just bad luck?

My husband and I have had 3 cycles of IVF(ICSI) with supposedly good quality embryos replaced
each time ( 8-10 cell at day 3) and spare ones to freeze which have later survived the thaw and been replaced. Hysteroscopy investigation showed everything normal, I have always responded well to stimulation drugs and no problems with the size of my lining. Can it just be bad luck and which further treatment would you recommend please?

Our Expert's Answer

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I am sorry to hear that you have been unsuccessful with 3 cycles of IVF and ICSI.  You did not mention how old you are as this may play a part in your lack of success.  You could try again.  I would suggest asking for the embryos to be kept until the blastocyst stage as this may give you more information on embryo development.  You could also have the embryos screened for abnormalities before they are replaced.  This is called Pre-implantation Genetic Screening or PGS.