Non-invasive prenatal chromosome testing (NIPT)
Pregnant but worried about possible chromosome conditions? We offer the very latest in non-invasive prenatal testing which assesses the risks of conditions such as Down’s Syndrome. Noninvasive prenatal tests like Serenity NIPT have been shown to perform better than traditional prenatal screening methods, and they avoid the risk of miscarriage associated with invasive diagnostic procedures like amniocentesis and chorionic villus sampling (CVS).
Anyone can come to us for this test, whether you’ve had successful treatment with us, at another clinic, or have conceived naturally.
What is the Serenity Non-Invasive Prenatal Test?
The new Serenity non-invasive prenatal test is a simple, non-invasive blood test. Available from 10 weeks of pregnancy, it involves a sample of your blood being taken by our nurses at our clinic. This sample is then sent for analysis to a specialist laboratory in the UK.
The test determines the risk to your baby of various Trisomies - chromosome conditions caused by three copies of a particular chromosome instead of two. DNA circulates from your baby in your own blood during pregnancy, Serenity analyses this DNA via your own blood.
The Serenity test assesses the risks of:
- Trisomy 13 (Patau Syndrome)
- Trisomy 18 (Edwards Syndrome)
- Trisomy 21 (Down’s Syndrome)
- Sex chromosome abnormalities such as Turner Syndrome
How many different Serenity Tests are there?
Serenity testing is offered as Serenity four different test 'panels', providing options to accommodate every patient’s unique situation. Serenity Basic and Serenity 24 are available for both singleton and twin pregnancies.
How accurate is the result of the Serenity NIP Test?
Serenity is an early and highly-accurate test which unlike traditional testing such as amniocentesis or CVS carries no risk to your baby. Studies show it is over 99% accurate for assessing Down’s Syndrome risk. The false positive and false negative results are also significantly lower than traditional invasive testing methods with a combined false positive rate for Trisomy 21, 18 and 13 of just 0.15%.
How long does the test take and how much does it cost?
Depending upon which Serenity test your chose, your results will either be available within 3-5 or 7-10 working days from testing, typically around the time you would go for your first trimester 12 week scan.
Deciding if the test is right for you
Serenity does not detect all fetal abnormalities. If your test result shows a high risk that your baby has a chromosome condition, it is not a definite diagnosis, although the accuracy of the Serenity test means it’s highly unlikely your test result would be inaccurate. In the event of a positive result, you’ll be referred back to your NHS care provider for follow-up testing.
Want to know more?
If you’d like to know more about the Serenity tests at Manchester Fertility, please visit Serenity NIPT.
You can also contact our Patient Advisors on 0161 300 2730 to make your booking.
* Warburton D, DallaireL, ThangaveluM, Ross L, Levin B, Kline J. Trisomy recurrence: a reconsideration based on North American data. Am J Hum Genet 2004;75(3):376-85.
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