Endometrial Receptivity Array

Endometrial Receptivity Array

Genetic testing to increase the chance of successful embryo implantation, in selected patients who have had several failed treatment cycles in the past.

Endometrial Receptivity Array (ERA) is a genetic test performed prior to frozen embryo transfer in highly-selected patients. This test aims to  identify the best time for your embryo transfer, based on genetic testing to identify the window of implantation.

ERA may be advised if:

  • You’ve had repeated implantation failure
  • You’ve had failed IVF cycles despite the transfer of good quality embryos

We are not completely sure whether the test improves the chance of success with IVF.

However, there are studies showing that the information available from an ERA test may benefit some groups of women.

How can ERA help me?

Your uterus is usually most receptive to an embryo around days 19-21 of your menstrual cycle, which is when embryo transfer is typically carried out.

But in some women, this window of implantation may in fact be earlier or later, and it is thought that this may lead to failure of IVF.

ERA is a test that allows us to assess whether or not the uterus is receptive at the usual time. Based on the results of the test, we can alter the time of embryo transfer, in the hope of increasing the chance of an embryo implanting successfully.  

How can ERA help me?

How ERA works

Endometrial biopsy

We will perform an endometrial biopsy in a cycle where you take hormones in a similar way to a frozen embryos transfer cycle, timed for when we think your uterus should be most receptive.

Tissue is preserved

The endometrial tissue is immediately transferred into a tube which contains a fluid that facilitates the preservation of the tissue and sent to a specialist genetics laboratory.

Genetic analysis

The laboratory analyses the genes involved in embryo receptivity to determine if your uterus is optimum for transfer. We then use this information to decide when your embryo transfer should be carried out in a future frozen embryo transfer cycle.

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"A huge thank you to the whole team at Manchester Fertility"

Isabel and Matthew, Jul 2018

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